2026 3Rs Sharing Conference Agenda
MORNING SESSION 9:00 am - Opening Remarks & Updates 9:05 am - The Critical Role of the 3Rs: Federal Projects & Updates Update on Complement-AIRE program & ORIVA Margaret Ochocinska, NIH FNIH's NAMs VQN: Pilots & Implementation Amber Zimmerman, FNIH AI & Replacements in Research: Scientific & Operational Efficiency Part I Enhancing Regulatory Protocol Quality through an Ethically Governed, AI-Assisted Review Framework Jeremy DeRicco, University of Pittsburgh 10:00 am - Networking Break & Exhibitor Connections 10:30 am - AI & Replacements in Research: Scientific & Operational Efficiency Part II
Replacing the second species Sally Thompson-Iritani, University of Washington Use of learning machines in drug discovery to fight lung diseases Deepak Deshpande & Raymond Penn, Thomas Jefferson University Prompting for AI Szczepan Baran, BaranCafe
11:30 - Networking Lunch AFTERNOON SESSION 12:30 pm - NAMs and Animals: Incorporating new methodologies into your research pipeline Stem Cell-based Primate In Vitro Models to Enhance Translational Relevance of Drug Safety Morteza Roodgar, Exir Bio Replacing Non-Human-Relevant Animal Studies with Liver Spheroids: A Case Study in Amcenestrant-Induced Hepatotoxicity Piyush Bajaj, Eli Lilly and Company Replacing sentinel animals for 3Rs and operational benefits Alicia Donnelly, Children's Hospital of Philadelphia 1:45 pm - The Forgotten R: Impactful Reduction Techniques Considerations of non-human primate use in nonclinical toxicity study package for oncology therapeutics with well-characterized target in support of 3Rs – an IQ DruSafe industry survey Timothy Hart, GSK Enormous Reduction effect through genetic STR analysis of chimeric sperm Ronald Naumann, Max Planck Institute of Molecular Cell Biology Precision cut lung slice cultures for Reduction in toxicology Julia Herbert, Rutgers University 2:45 pm - Networking Break & Exhibitor Connections 3:15 pm - Digital Measures, & Other Refinements for Science & Welfare Non-invasive home cage monitoring of body temperature and activity for the evaluation of novel mouse enrichment nesting materials Vic Johnson, BRT Labs Surgical refinements for laboratory animals Kristin Gardiner, University of Pennsylvania Using positive reinforcement for refinement and cost savings in pigs Emma Halter, University of Pennsylvania 4:15 - 5:15 pm – Conference Wrap-up and Networking Reception **Presentation Titles Preliminary** |